It pretty much looks like a done deal. The Astros will be moving to the American League West. In 2013, the alignment would look like this:
Watching them on TV will be a bit easier. Now, all 5 teams in the NL West are 1 to 2 hours behind. In the AL, only 3 teams will be west of the Astros. For me, the novelty of seeing the Astros play American League teams I hardly ever see will probably be enough to keep me interested for awhile, but the team will have to be better to sustain any interest.